Gender Dependency in the Pathogenesis of Cardiac Hypertrophy
نویسندگان
چکیده
منابع مشابه
Gender dependency in the pathogenesis of cardiac hypertrophy: effect of norepinephrine on transforming growth factor-beta release in female heart.
Representing the most numerous nonmyocytes in the myocardium, adult cardiac fibroblasts (and myofibroblasts) function to synthesize fibrillar collagens and thus maintain the integrity of the cardiac extracellular matrix (matrix). Matrix remodeling is manifest as interstitial fibrosis of the remnant heart or the progressive evolution of the structure of the infarct scar in the etiology of post-m...
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15 صفحه اولHypertrophy, pathology, and molecular markers of cardiac pathogenesis.
Increased ventricular expression of several genes, including atrial natriuretic factor (ANF), has been documented in experimental models of cardiac hypertrophy. It remains to be clarified whether altered expression of these genes is a consistent marker of the hypertrophy itself or a marker of some parallel pathogenetic process. Using a transgenic mouse model of hypertrophic cardiomyopathy as a ...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2004
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000141484.53649.6f